Physiological selection with hyaluronic acid (physiological ICSI)
In this method, the washed sperm cells are put into contact with hyaluronic acid, a biological polymer which is also found in the gel-like outer layers of the human egg. Mature sperm cells do have docking sites (receptors) on their heads and stick to hyaluronic acid, while the tail moves vigorously, much alike natural fertilisation. According to research work performed at Yale University, the sperm cells selected with this method are more mature, have less defects in the genetic code substance DNA and possess more often the correct number of chromosomes, i.e. are genetically superior.
We recommend functional (physiological) selection in the following situations:
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- extremely little sperm cells of normal shape (unter 4%);
- several failed attempts at IVF without implantation;
- known genetic problem of the sperm cells, like increased DNA fragmentation;
- history of several early miscarriages.
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The special selection method represents an additional effort by the biologist as well as additional material, which is why we have to charge a moderate surcharge. We would be happy to give you additional information personally.